KMID : 0191120120270030329
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Journal of Korean Medical Science 2012 Volume.27 No. 3 p.329 ~ p.331
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Unexpected Fatal Hypernatremia after Successful Cardiopulmonary Resuscitation with Therapeutic Hypothermia: A Case Report
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Choi Sang-Sik
Kim Won-Young Kim Won Lim Kyung-Su
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Abstract
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Central diabetes insipidus (DI), characterized by unexpected fatal hypernatremia, is a rare complication after successful cardiopulmonary resuscitation with therapeutic hypothermia, but may be potentially fatal if recognition is delayed. We describe here a patient who experienced cardiac arrest due to a pulmonary embolism, followed by successful resuscitation after induction of therapeutic hypothermia. The patient, however, suddenly developed unexpected hypernatremia with increased urine output and was diagnosed with central DI as a complication of cerebral edema, and eventually died. Our findings suggest that central DI should be considered as a possible complication following unexpected hypernatremia with increased urine output during therapeutic hypothermia and that desmopressin acetate should be used to treat central DI.
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KEYWORD
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Hypernatremia, Diabetes Insipidus, Hypoxia, Brain, Hypothermia, Induced
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