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KMID : 0191120120270030329
Journal of Korean Medical Science
2012 Volume.27 No. 3 p.329 ~ p.331
Unexpected Fatal Hypernatremia after Successful Cardiopulmonary Resuscitation with Therapeutic Hypothermia: A Case Report
Choi Sang-Sik

Kim Won-Young
Kim Won
Lim Kyung-Su
Abstract
Central diabetes insipidus (DI), characterized by unexpected fatal hypernatremia, is a rare complication after successful cardiopulmonary resuscitation with therapeutic hypothermia, but may be potentially fatal if recognition is delayed. We describe here a patient who experienced cardiac arrest due to a pulmonary embolism, followed by successful resuscitation after induction of therapeutic hypothermia. The patient, however, suddenly developed unexpected hypernatremia with increased urine output and was diagnosed with central DI as a complication of cerebral edema, and eventually died. Our findings suggest that central DI should be considered as a possible complication following unexpected hypernatremia with increased urine output during therapeutic hypothermia and that desmopressin acetate should be used to treat central DI.
KEYWORD
Hypernatremia, Diabetes Insipidus, Hypoxia, Brain, Hypothermia, Induced
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